At present, there are multiple treatments available for attention-deficit/hyperactivity disorder (ADHD), a neurodevelopmental condition that can lead to attention problems, hyperactivity, and impulsiveness in both adults and children. Stimulant drugs are frequently recommended medical treatment for ADHD. These drugs elevate the levels of specific neurotransmitters in the brain to enhance concentration and focus while aiding in minimizing hyperactive and impulsive actions.
Vyvanse (lisdexamfetamine) and Adderall (a combination of amphetamine and dextroamphetamine) are among the most frequently prescribed medications for ADHD. Both are stimulant medications that affect the central nervous system, yet they function through distinct mechanisms. Both medications can be effective, yet there is a difference between Adderall and Vyvanse that can make one more suitable than the other. Vyvanse and Adderall are designated as controlled substances by the United States Drug Enforcement Administration within the Schedule II category, signifying that they are subject to strict regulations for drugs that individuals can obtain only with a physician’s prescription. Moreover, this categorization indicates that both of these substances are viewed as having a considerable likelihood of physical dependence in users, marking them as high-risk for misuse. So, if you’re asking yourself about the difference between Vyvanse vs. Adderall, this article will help you understand what sets both these medications apart.What Are Vyvanse and Adderall?
Vyvanse vs Adderall are medications utilized for the treatment of attention deficit hyperactivity disorder (ADHD). They are both stimulants known as amphetamines. They function by increasing the amounts of chemicals in the brain known as dopamine and norepinephrine, which aid in enhancing focus, impulse control, and attention during school or work. Adderall was first approved by the FDA in 1996, followed by Adderall XR—a longer-lasting, once-daily version with the same chemical formulation—in 2002. Vyvanse received FDA approval in 2007. Unlike Adderall, Vyvanse is not approved for children under 6 years old, but it is authorized for treating binge eating disorder in adults 18 and older. Adderall, meanwhile, is also approved to treat narcolepsy, a type of sleep disorder. Although both Vyvanse and Adderall XR are types of amphetamines, they differ significantly in composition. Adderall contains two amphetamine salts: amphetamine sulfate (25%) and dextroamphetamine sulfate (75%). Vyvanse contains a compound known as lisdexamfetamine. Adderall works by blocking the reabsorption of specific neurotransmitters, dopamine and norepinephrine, while also releasing additional amounts of these chemicals from their storage sites [1]. The lisdexamfetamine in Vyvanse, on the other hand, is inactive until it is metabolized by the body and converted into dextroamphetamine, which then increases dopamine and norepinephrine levels in the central nervous system [2]. Overall, the main differences between Adderall vs. Vyvanse lie in their metabolic processes in the body, the frequency of administration required, and their anticipated likelihood of being misused.Vyvanse vs. Adderall Dosages
Adderall is available in capsule form, packed with beads containing the two salts, referred to as mixed amphetamine salts. An Adderall capsule ranges from 5 to 30 milligrams. A dose of the original immediate-release form of the drug remains effective in one’s system for roughly 4 hours. The extended-release version, Adderall XR, is available in the same dosages but can last for 8 to 12 hours. This is because half of the beads act quickly, while the other half act slowly. Vyvanse is available in capsule form, ranging from 10 to 70 milligrams of medication, as well as chewable tablets, ranging from 10 to 60 milligrams of medication. Vyvanse contains the stimulant amphetamine along with a substance known as lysine. The body needs to process the lysine to reach the stimulant, which means a single dose could last as long as 14 hours. In certain situations, your physician may recommend that you use both long-acting and short-acting stimulants for comprehensive coverage throughout the day. For instance, taking a long-acting dose in the morning and a short-acting dose later in the afternoon [3].Vyvanse vs. Adderall Side Effects
If you’re asking yourself, is Vyvanse safer than Adderall, remember that both are stimulant drugs with known side effects [4] and addiction risks. Side effects may include:- Blurred vision
- Dry mouth
- Dizziness
- Stomach upset or pain
- Headaches
- Higher blood pressure
- Tics
- Insomnia
- Mood swings
- Loss of appetite
- Anxiety or panic attacks
- Paranoia
- Hallucination
- Irritability
- Diarrhea
- Weight loss
- Restlessness
- Constipation
- Tremors
- Hives
- Vomiting
- Skin rash
- Increased heart rate
- Palpitations
Sexual Side Effects
In some cases, men may experience difficulties achieving or maintaining erections, more frequent erections, or longer-lasting erections than usual. In clinical trials, 2% to 4% of adults taking Adderall XR reported sexual side effects, including erectile difficulties and reduced sexual interest. Research on Vyvanse showed that about 2% of men experienced erectile dysfunction, while just over 1% of all adults (male and female) reported a decreased interest in sexual activity [5, 6].Vyvanse vs Adderall: Costs
Your doctor will suggest a medication depending on its effectiveness for your particular circumstances. Use this opportunity to discuss medication expenses. Inquiring with your doctor about switching to a different medication to reduce expenses might require dosage modifications and adjustments, ultimately influencing costs as well. The price of any medication can differ significantly depending on the type and amount. Typically, generic versions of the drug are considerably cheaper than brand-name products. Additionally, pharmacies may offer varying prices for medications as well. Verify with your insurance policy to understand what is included. A month’s supply of Vyvanse vs Adderall XR without insurance can cost between $150 to $400 based on specific factors like frequency and dosage. Drug shortages also affect the cost and availability of stimulant drugs.Vyvanse Costs
Previously, Vyvanse was exclusively offered as a name-brand prescription medication, which frequently resulted in a higher cost compared to other drugs, but it is now available in generic versions. Brand-name Vyvanse is about $19 per tablet, while the generic version works out to roughly $2.67 per 30mg capsule.Adderall Costs
The cost of brand-name Adderall is usually around $11 per tablet and about $20 to $30 for 30 generic Adderall 20 mg capsules or fewer.Are Vyvanse and Adderall Addictive?
If you’re considering whether Vyvanse is better than Adderall in terms of safety or misuse, most central nervous system stimulants are categorized as regulated substances, indicating they can be equally abused and may result in substance use disorders, such as addiction [7]. Certain states have also restricted the quantity you can purchase in a single transaction to reduce misuse. Adderall immediate-release has a higher potential of being abused because it contains free amphetamine salts. On the contrary, this is less probable with Adderall XR vs Vyvanse, as they are formulated to release their active ingredients gradually. This is particularly relevant for Vyvanse, since the body must first metabolize the lysine before it reaches the stimulant component of the medication. However, you and your physician should talk about the risks and advantages of different treatment options before determining which medication is most suitable for your circumstances.Is Vyvanse Stronger Than Adderall?
Let’s now address the most commonly asked question: Is adderall stronger than vyvanse? Adderall vs Vyvanse have both been clinically tested to alleviate disruptive symptoms associated with Attention Deficit Hyperactivity Disorder (ADHD). Various studies have shown that Adderall is highly effective for conditions like attention deficits, hyperactivity, impulsiveness, and aggressive behavior. Additionally, an analysis of 20 studies revealed that in adults, ADHD symptoms significantly improved with either lisdexamfetamine (Vyvanse) or mixed amphetamine salts (Adderall), although the effects were somewhat greater with Vyvanse [8]. Research comparing Adderall vs Vyvanse against placebo (a non-effective pill) or against other ADHD medications established that both Adderall and Vyvanse enhance several ADHD symptoms [9]. Investigators did not determine one drug to be superior to the other, and side effects like reduced appetite, sleep difficulties, and stomach issues were prevalent yet comparable across various formulations. This means that when choosing between Adderall or Vyvanse or wondering “Is adderall stronger than vyvanse?”, it’s essential to recognize that the effects of medication vary significantly among individuals. Hence, it’s advisable to discuss with your doctor the most suitable medication option for you or your child. For instance, children in school frequently require medications with a shorter duration of action to ensure they obtain sufficient sleep, and Vyvanse is not available in a short-acting version.Vyvanse and Adderall Interactions
Another aspect to think about when deciding between Vyvanse and Adderall is how they could interact with additional medications you are taking. Warnings regarding possible interactions are included in the patient information leaflet that accompanies the medication. Since Adderall, Adderall XR, and Vyvanse are all classified as amphetamines, they have similar interactions with numerous other medications. Several medications that could interact with Adderall, Adderall XR, and Vyvanse, involving additional oversight or adjustments in treatment, are: Acidifying agents: These consist of ascorbic acid and juices from fruits. These acidic substances may reduce the quantity of medication that the body absorbs. Alkalinizing agents. Alkalizing substances counteract acids, so they could enhance the body’s uptake of these medications. This includes sodium bicarbonate, the key component of baking soda. Monoamine oxidase inhibitors (MOIs): People using stimulants such as Adderall and Vyvanse in conjunction with MAOIs, a distinct type of antidepressant, must be closely observed. This combination of medications can lead to serious health issues in some individuals. Opioids: Combining a stimulant such as Adderall or Vyvanse with an opioid like Vicodin or OxyContin can lead to physical and psychological issues, including dependency. Patients who have been given both types of medications should be carefully observed by their physician. Some other medications that can interact with Adderall vs Vyvanse include blood pressure medications, antihistamines, and seizure drugs (including phenobarbital and phenytoin). Additionally, proton pump inhibitors for heartburn don’t affect Vyvanse but do delay the increase of Adderall XR levels in the bloodstream.FAQs
Is Vyvanse better for you than Adderall?
Both Vyvanse and Adderall are highly effective medications for the treatment of ADHD. However, which medication is better for you depends on your individual circumstances and prior health issues.Does Vyvanse give you energy like Adderall?
Like Adderall, Vyvanse stimulates the nervous system, resulting in heightened energy and alertness.Do you lose more weight on Vyvanse or Adderall?
Medications such as Adderall and Vyvanse may suppress appetite and result in weight loss. In children, they can hinder growth. These medications are not sanctioned for weight loss, and the use of similar drugs for this reason has been associated with significant cardiac risks.Why is Vyvanse so popular?
Vyvanse is highly effective in alleviating symptoms linked to ADHD, including challenges with concentration and attention, along with hyperactivity and impulsivity. Vyvanse was also the first medication authorized by the Food and Drug Administration (FDA) for treating binge-eating disorder in adults.What is 40 mg of Vyvanse equal to in Adderall?
Although the exact potency comparisons vary based on individual response, 40mg of Vyvanse is considered equal to about 12- 15mg of Adderall.Vyvanse vs Adderall XR, which is stronger?
Despite there being limited studies comparing the two medications, an analysis of 20 studies found that in adults, the improvement of ADHD symptoms was significantly greater with Vyvanse.Is Vyvanse Adderall?
No. Vyvanse and Adderall are stimulant drugs used in the treatment of ADHD, but their compositions vary significantly. Vyvanse consists of lisdexamfetamine, whereas Adderall is a combination of amphetamine and dextroamphetamine.Get Help for Stimulant Medication Abuse at California Detox
Numerous individuals misuse prescription medications and stimulants to enhance their concentration and alertness for school, work, or various responsibilities. Unfortunately, this frequently results in addiction due to misuse, such as taking medication without a prescription or exceeding the prescribed amount. Additionally, stopping Vyvanse or Adderall suddenly after substance abuse can lead to withdrawal symptoms that might necessitate professional assistance. If you’re having difficulties with dependence on Vyvanse or Adderall, California Detox can help. Our addiction treatment experts provide a variety of effective therapies for those pursuing sobriety. Our team will create a customized plan that may include the following:- Medication management.
- One-to-one counseling.
- Family therapy.
- Group therapy.
- Behavioral therapy.
- Motivational therapy.
- Holistic treatment.
- Aftercare planning.






