Is Mixing Hallucinogens and Alcohol Dangerous?

Table of Contents


Mixing hallucinogens and alcohol is extremely risky. When these substances are used together, they can lead to severe health issues and increase the likelihood of developing concurrent addictions.

Effects of Mixing Alcohol and Hallucinogens

Alcohol is the most abused addictive substance in the United States, with alcohol abuse damaging individuals, families, and communities.

We want to help

Let’s setup a call and figure out the best treatment options for you or your loved one. Our detox specialists will get back to you immediately.

Hallucinogens, a category of drugs known for altering perception, carry significant risks and potential for addiction. They are not simply recreational substances and become even more hazardous when combined with alcohol. Consuming hallucinogens and alcohol simultaneously can have dangerous effects on both physical and mental health.

The group of substances referred to as hallucinogens includes various drugs that alter the person’s perception of reality, mainly through causing hallucinations. Hallucinations are false perceptions or distortions of what is actually present.

Additionally, some hallucinogens are classified as dissociative drugs, which can cause people to feel disconnected from reality. Certain dissociative hallucinogens may lead to loss of self-control, resulting in violent or reckless behaviors. Well-known hallucinogens that are non-dissociative include psilocybin mushrooms, LSD, DMT (found in ayahuasca), mescaline (derived from peyote), and. PCP and ketamine are common dissociative drugs. These are all controlled substances in the United States.

The unpredictable nature of hallucinogens means that their interaction with alcohol is also highly uncertain. Nevertheless, it’s clear that combining alcohol with hallucinogens like DMT, LSD, or peyote, can be extremely risky. People who use these hallucinogens while consuming alcohol may experience adverse effects like nausea, vomiting, dizziness, headaches, and panic attacks. This mix can also lead to increased heart rate and, in more severe cases, loss of consciousness or seizures. When some hallucinogens like MDMA are mixed with alcohol, there is also a risk of dangerously elevated body temperatures.

Beyond this, alcohol can amplify the negative aspects of a hallucinogen experience. It may intensify frightening hallucinations and deepen feelings of depression associated with distressing trips. Hallucinogens often affect self-awareness, which can lead some people to underestimate their alcohol consumption, increasing the risk of alcohol poisoning.

Also, the combination of these substances can impair judgment significantly. This impairment raises the likelihood of reckless behaviors, posing a danger not only to the person but also to others, especially in scenarios like driving. The convergence of altered perception from hallucinogens and the disinhibition from alcohol creates a potentially dangerous scenario with consequences extending beyond the person using hallucinogens.

Risks of Mixing Hallucinogenic Mushrooms and Alcohol

Combining hallucinogenic mushrooms containing psilocybin with alcohol is extremely risky and can lead to a range of adverse effects. Understanding these risks is beneficial for anyone who is thinking about mixing these substances. The key dangers include:

  • Unpredictable interactions: The interaction between alcohol and psilocybin is unpredictable. It can lead to unusual and potentially dangerous reactions, making it difficult to manage the effects and challenging to seek appropriate help in case of a bad reaction.
  • Diminished effects of each substance: Combining LSD with alcohol can diminish the noticeable effects of alcohol, potentially leading to excessive drinking. Increased consumption heightens the risk of encountering typical alcohol-related dangers like severe hangovers or alcohol poisoning.
  • Potential psychological distress: The combination of alcohol and hallucinogenic mushrooms can result in an intense and potentially overwhelming experience. This may lead to severe psychological distress or inflame pre-existing mental health conditions.
  • Intensified psychological effects: Hallucinogenic mushrooms can cause intense alterations in perception, mood, and thought patterns. When mixed with alcohol, these effects can be amplified, leading to increased confusion, anxiety, and paranoia.
  • Loss of coordination and judgment: Alcohol impairs judgment and motor coordination. When combined with the disorienting effects of hallucinogenic mushrooms, this can lead to dangerous situations, including accidents and injuries.
  • Nausea and vomiting: Both substances can cause gastrointestinal upset. Combining them may increase the likelihood of nausea and vomiting, which can be particularly distressing during a psychedelic experience.
  • Increased risk of overheating and dehydration: Psilocybin can affect the body’s ability to regulate temperature, and alcohol can lead to dehydration. Using the substances together may increase the risk of overheating or dehydration, which can have serious health implications.

Given these risks, it is advisable to avoid mixing hallucinogenic mushrooms with alcohol. This precaution helps to reduce the potential for negative health outcomes and ensures a safer experience for those choosing to use these substances.

What to Do If You Mixed Hallucinogenic Mushrooms and Alcohol

If you or someone you know has mixed hallucinogenic mushrooms with alcohol, take the following steps to ensure safety and address any potential risks:

1) Stay in a safe place

Remain in a place where you feel safe and comfortable. Avoid situations that could be overwhelming or dangerous.

2) Rest and hydrate

Drink water to stay hydrated, especially if you are experiencing nausea or vomiting. Try to rest in a calm and quiet area.

3) Stop consuming alcohol and hallucinogens

Avoid consuming more alcohol, mushrooms, or any other substances to prevent worsening the situation.

4) Monitor symptoms

Monitor any symptoms you experience. Symptoms like severe anxiety, paranoia, hallucinations, or physical discomfort may manifest.

5) Seek medical attention if appropriate

If you or the person experiences severe reactions, such as difficulty breathing, chest pain, extreme confusion, or seizures, seek medical help immediately.

6) Have someone with you

It’s advisable to not be alone. Have a friend or someone you trust stay with you to keep an eye on your condition and help if your situation worsens.

7) Remain calm

Remember that the effects are temporary. Try to stay calm and remind yourself that the sensations will pass.

8) Avoid driving

Your perception and motor skills might be impaired, so do not drive or engage in activities that require coordination and focus.

9) Learn from the experience

Once the effects have worn off, take some time to reflect on the experience and consider the risks involved in mixing these substances. This can help prevent the same thing happening again.

10) Consider engaging with professional treatment

If you frequently mix hallucinogenic mushrooms and alcohol, it might pay to seek professional advice or counseling to address this behavior.

Remember, the combination of hallucinogenic mushrooms and alcohol can trigger unpredictable and potentially harmful effects. Taking these steps can help manage the immediate risks, but it’s also important to consider long-term strategies for safer substance use or abstinence.

Get Treatment for Alcohol Addiction at California Detox

Although hallucinogen addiction is not as common as alcohol addiction, it is nevertheless possible to develop problematic patterns of consumption to this class of drugs. Regardless of the addictions you are battling, we can help you recalibrate your life at California Detox in Laguna Beach, CA.

Addiction treatment normally begins with supervised detoxification. Our medical detox programs provide access to FDA-approved medications that streamline the intensity of withdrawal. You will also benefit from continuous clinical care, mitigating the potentially disruptive influence of complications and relapse. Following detox, you’ll move into ongoing inpatient treatment at our luxury beachside facility.

During inpatient treatment at California Detox, you can engage with an individualized array of therapies that may include:

  • Psychotherapies like CBT and DBT
  • MAT (medication-assisted treatment)
  • Individual counseling
  • Group therapy
  • Family therapy
  • Holistic interventions
  • Aftercare and support

When you are ready to address alcohol and cocaine addiction in California, dial 949.694.8305 right away.


Alcohol is a central nervous system depressant while hallucinogens are a category of drugs known as psychoactive drugs.
Yes, mixing the two drugs can make you more dependent on them, increasing addictive potential


Request a Call